Bacterial vaginosis (BV) is the most common cause of abnormal vaginal discharge in women of childbearing age worldwide.(1) It typically occurs in sexually active women, and is associated with douching, early age at first sexual intercourse, inconsistent condom use, higher number of sexual partners, or recent partner change. For women who have sex with women (WSW) bacterial vaginosis is associated with increased numbers of recent and past female partners and with confirmed bacterial vaginosis in a female partner.(2) BV is less common when male partners are circumcised.(2)
Bacterial vaginosis is a polymicrobial condition, characterised by an overgrowth of anaerobic organisms that replace normal lactobacilli, leading to an increase in vaginal pH (≥4.5). This may lead to an increase in vaginal discharge and a change in odour, often described as a fishy or ammonia-like smell. However, up to 50 per cent of women with BV are asymptomatic.(3)
Gardnerella vaginalis is the most commonly found bacteria in BV. Other organisms associated with BV include Atopobium vaginae, Prevotella species, Mycoplasma hominis and Mobiluncus species. Despite growing understanding of its physiology and sequelae, the precise pathogenesis of BV is controversial and its aetiology, pathology, microbiology and transmission are still poorly understood.(4) BV ...
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Symptoms
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Diagnosis
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Amsel’s criteria
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Complications
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Management
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Recommended antibiotic treatment regimens for bacterial vaginosis
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Recurrent bacterial vaginosis
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Bacterial vaginosis in pregnancy
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Resources – Bacterial vaginosis
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1.
Madhivanan P, Krupp K, Chandrasekaran V, Karat C, Arun A, Cohen CR, et al. Prevalence and correlates of Bacterial Vaginosis among young women of reproductive age in Mysore, India. Indian J Med Microbiol. 2008; 26(2):132-7.
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2.
Forcey D, Vodstrcil LA, Hocking JS, Fairley CK, Law M, McNair RP, et al. Factors associated with Bacterial Vaginosis among women who have sex with women: a systematic review. PLoS ONE. 2015; 10(12):e141905.
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4.
Pirotta M, Fethers KA, Bradshaw CS. Bacterial Vaginosis: more questions than answers. Aust Fam Physician. 2009; 38(6):394-7.
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5.
Gottschick C, Zhi-Luo D, Vital M, Clarissa M, Abels C, Pieper DH, et al. Treatment of biofilms in Bacterial Vaginosis by an amphoteric tenside pessary-clinical study and microbiota analysis. Microbiome. 2017; 5(119).
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7.
2015 Sexually Transmitted Disease Treatment Guidelines [Internet]. Centers for Disease Control and Prevention; 2015. Disease Characterized by Vaginal Discharge; [updated 2015 June 4; cited 2015 July 14]. Available from: https://www.cdc.gov/std/tg2015/vaginal-discharge.htm.
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9.
Bradshaw C, Morton AN, Hocking J, Garland SM, Morris LM, Moss LM, et al. High recurrence rates of bacterial vaginosis over the course of 12 months after oral metronidazole therapy and factors associated with recurrence. J Infect Dis. 2006; 193(11):1478-86.
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10.
Car P. Chronic vaginal discharge: causes and management O&G. 2014; 16(3).
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11.
Saxon C, Edwards A, Rautemaa-Richardson R, Owen C, Nathan B, Plamer B et al. British Association for Sexual Health and HIV national guideline for the management of vulvovaginal candidiasis (2019).[Internet]. British Association for Sexual Health and HIV: Clinical Effectiveness Group (CEG). 2019. Available from: https://www.bashhguidelines.org/media/1223/vvc-2019.pdf.
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12.
Fischer G. Coping with chronic vulvovaginal candidiasis. Medicine Today. 2014; 15(2):33-40.
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13.
Matheson A, Mazza D. Recurrent vulvovaginal candidiasis: A review of guideline recommendations. Aust N Z J Obstet Gynaecol. 2017; 57(2):139-45.
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21.
Fischer G, Bradford J. The Vulva: a Practical Handbook for Clinicians. 2nd Ed. Sydney, Australia: Cambridge University Press; 2016.
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22.
Nunns D, Mandal D, Byren M, McLelland J, Rani R, Cullimore J, et al. Guidelines for the management of vulvodynia. British Journal of Dermatology. 2010;162(6):1180-5.
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23.
Lynch PJ, Moyal-Barrocco M, Bogliatto F, Micheletti L, Scurry J. ISSVD classifications of vulvar dermatoses: pathologic subsets and their clinical correlates. J Reprod Med. 2007; 52(1): 3-9.
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25.
Ampt A, Roach V, Roberts CL. Vulvoplasty in New South Wales, 2001–2013: a population-based record linkage study. Med J Aus. 2016;205(8):365-9.
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